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Proteasome malfunction activates macroautophagy in the heart

Protein quality control (PQC) senses and repairs misfolded/unfolded proteins and, if the repair fails, degrades the terminally misfolded polypeptides through an intricate collaboration between molecular chaperones and targeted proteolysis. Proteolysis of damaged proteins is performed primarily by th...

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Bibliografiska uppgifter
Huvudupphovsmän: Zheng, Qingwen, Su, Huabo, Tian, Zongwen, Wang, Xuejun
Materialtyp: Artigo
Språk:Inglês
Publicerad: e-Century Publishing Corporation 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3211094/
https://ncbi.nlm.nih.gov/pubmed/22081794
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