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Proteasome malfunction activates macroautophagy in the heart

Protein quality control (PQC) senses and repairs misfolded/unfolded proteins and, if the repair fails, degrades the terminally misfolded polypeptides through an intricate collaboration between molecular chaperones and targeted proteolysis. Proteolysis of damaged proteins is performed primarily by th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zheng, Qingwen, Su, Huabo, Tian, Zongwen, Wang, Xuejun
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3211094/
https://ncbi.nlm.nih.gov/pubmed/22081794
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