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Relipidated tissue factor linked to collagen surfaces potentiates platelet adhesion and fibrin formation in a microfluidic model of vessel injury

Microfluidic devices allow for the controlled perfusion of human or mouse blood over defined prothrombotic surfaces at venous and arterial shear rates. To mimic in vivo injuries such a plaque rupture, the need exists to link lipidated tissue factor (TF) to surface bound collagen fibers. Recombinant...

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Detalhes bibliográficos
Main Authors: Colace, Thomas V., Jobson, Jennielle, Diamond, Scott L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3211088/
https://ncbi.nlm.nih.gov/pubmed/21902184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc200326v
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