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Relipidated tissue factor linked to collagen surfaces potentiates platelet adhesion and fibrin formation in a microfluidic model of vessel injury

Microfluidic devices allow for the controlled perfusion of human or mouse blood over defined prothrombotic surfaces at venous and arterial shear rates. To mimic in vivo injuries such a plaque rupture, the need exists to link lipidated tissue factor (TF) to surface bound collagen fibers. Recombinant...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Colace, Thomas V., Jobson, Jennielle, Diamond, Scott L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3211088/
https://ncbi.nlm.nih.gov/pubmed/21902184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc200326v
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