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Ethanol and Reactive Species Increase Basal Sequence Heterogeneity of Hepatitis C Virus and Produce Variants with Reduced Susceptibility to Antivirals

Hepatitis C virus (HCV) exhibits a high level of genetic variability, and variants with reduced susceptibility to antivirals can occur even before treatment begins. In addition, alcohol decreases efficacy of antiviral therapy and increases sequence heterogeneity of HCV RNA but how ethanol affects HC...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Seronello, Scott, Montanez, Jessica, Presleigh, Kristen, Barlow, Miriam, Park, Seung Bum, Choi, Jinah
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210796/
https://ncbi.nlm.nih.gov/pubmed/22087316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027436
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