Ethanol and Reactive Species Increase Basal Sequence Heterogeneity of Hepatitis C Virus and Produce Variants with Reduced Susceptibility to Antivirals

Hepatitis C virus (HCV) exhibits a high level of genetic variability, and variants with reduced susceptibility to antivirals can occur even before treatment begins. In addition, alcohol decreases efficacy of antiviral therapy and increases sequence heterogeneity of HCV RNA but how ethanol affects HC...

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Detaylı Bibliyografya
Asıl Yazarlar: Seronello, Scott, Montanez, Jessica, Presleigh, Kristen, Barlow, Miriam, Park, Seung Bum, Choi, Jinah
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210796/
https://ncbi.nlm.nih.gov/pubmed/22087316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027436
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