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Predicting drug resistance of the HIV-1 protease using molecular interaction energy components
Drug resistance significantly impairs the efficacy of AIDS therapy. Therefore, precise prediction of resistant viral mutants is particularly useful for developing effective drugs and designing therapeutic regimen. In this study, we applied a structure-based computational approach to predict mutants...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3210569/ https://ncbi.nlm.nih.gov/pubmed/18704937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22192 |
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