Llwytho...

Predicting drug resistance of the HIV-1 protease using molecular interaction energy components

Drug resistance significantly impairs the efficacy of AIDS therapy. Therefore, precise prediction of resistant viral mutants is particularly useful for developing effective drugs and designing therapeutic regimen. In this study, we applied a structure-based computational approach to predict mutants...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hou, Tingjun, Zhang, Wei, Wang, Jian, Wang, Wei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210569/
https://ncbi.nlm.nih.gov/pubmed/18704937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22192
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