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In vivo variation in metabotropic glutamate receptor subtype 5 binding using positron emission tomography and [(11)C]ABP688

The metabotropic glutamate receptor subtype 5 (mGluR5) has been implicated in the pathophysiology of mood and anxiety disorders. Recently, a positron emission tomography (PET) tracer exhibiting high selectivity and specificity for mGluR5, 3-(6-methyl-pyridin-2-ylethynyl)-cyclohex-2-enone-O-(11)C-met...

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Autori principali: DeLorenzo, Christine, Kumar, J S Dileep, Mann, J John, Parsey, Ramin V
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210337/
https://ncbi.nlm.nih.gov/pubmed/21792244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.105
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