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Modeling Considerations for In Vivo Quantification of the Dopamine Transporter Using [(11)C]PE2I and Positron Emission Tomography

The dopamine transporter (DAT) is an important imaging target since changes in DAT have been implicated in a variety of neurological and psychiatric disorders and can result from certain classes of medications. [(11)C]PE2I, a radioligand with high specificity for DAT, has been shown to exhibit favor...

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Bibliographic Details
Main Authors: DeLorenzo, Christine, Kumar, J. S. Dileep, Zanderigo, Francesca, Mann, J. John, Parsey, Ramin V.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757108/
https://ncbi.nlm.nih.gov/pubmed/19458606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.49
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