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Alzheimer's Disease and Non-Demented High Pathology Control Nonagenarians: Comparing and Contrasting the Biochemistry of Cognitively Successful Aging

The amyloid cascade hypothesis provides an economical mechanistic explanation for Alzheimer's disease (AD) dementia and correlated neuropathology. However, some nonagenarian individuals (high pathology controls, HPC) remain cognitively intact while enduring high amyloid plaque loads for decades...

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書誌詳細
主要な著者: Maarouf, Chera L., Daugs, Ian D., Kokjohn, Tyler A., Walker, Douglas G., Hunter, Jesse M., Kruchowsky, Jane C., Woltjer, Randy, Kaye, Jeffrey, Castaño, Eduardo M., Sabbagh, Marwan N., Beach, Thomas G., Roher, Alex E.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210154/
https://ncbi.nlm.nih.gov/pubmed/22087282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027291
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