Subjects harboring presenilin familial Alzheimer’s disease mutations exhibit diverse white matter biochemistry alterations

Alzheimer’s disease (AD) dementia impacts all facets of higher order cognitive function and is characterized by the presence of distinctive pathological lesions in the gray matter (GM). The profound alterations in GM structure and function have fostered the view that AD impacts are primarily a conse...

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Detalhes bibliográficos
Main Authors: Roher, Alex E, Maarouf, Chera L, Malek-Ahmadi, Michael, Wilson, Jeffrey, Kokjohn, Tyler A, Daugs, Ian D, Whiteside, Charisse M, Kalback, Walter M, Macias, MiMi P, Jacobson, Sandra A, Sabbagh, Marwan N, Ghetti, Bernardino, Beach, Thomas G
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783832/
https://ncbi.nlm.nih.gov/pubmed/24093083
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