Alzheimer's Disease and Non-Demented High Pathology Control Nonagenarians: Comparing and Contrasting the Biochemistry of Cognitively Successful Aging

The amyloid cascade hypothesis provides an economical mechanistic explanation for Alzheimer's disease (AD) dementia and correlated neuropathology. However, some nonagenarian individuals (high pathology controls, HPC) remain cognitively intact while enduring high amyloid plaque loads for decades...

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Bibliografische gegevens
Hoofdauteurs: Maarouf, Chera L., Daugs, Ian D., Kokjohn, Tyler A., Walker, Douglas G., Hunter, Jesse M., Kruchowsky, Jane C., Woltjer, Randy, Kaye, Jeffrey, Castaño, Eduardo M., Sabbagh, Marwan N., Beach, Thomas G., Roher, Alex E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2011
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210154/
https://ncbi.nlm.nih.gov/pubmed/22087282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027291
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