Chargement en cours...

Concurrent HDAC and mTORC1 Inhibition Attenuate Androgen Receptor and Hypoxia Signaling Associated with Alterations in MicroRNA Expression

Specific inhibitors towards Histone Deacetylases (HDACs) and Mammalian Target of Rapamycin Complex 1 (mTORC1) have been developed and demonstrate potential as treatments for patients with advanced and/or metastatic and castrate resistant prostate cancer (PCa). Further, deregulation of HDAC expressio...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ellis, Leigh, Lehet, Kristin, Ramakrishnan, Swathi, Adelaiye, Remi, Miles, Kiersten M., Wang, Dan, Liu, Song, Atadja, Peter, Carducci, Michael A., Pili, Roberto
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210144/
https://ncbi.nlm.nih.gov/pubmed/22087262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027178
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!