A systematic analysis of Drosophila TUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors

PIWI proteins and their bound PIWI-interacting RNAs (piRNAs) form the core of a gonad-specific small RNA silencing pathway that protects the animal genome against the deleterious activity of transposable elements. Recent studies linked the piRNA pathway to TUDOR biology as TUDOR domains of various p...

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Hlavní autoři: Handler, Dominik, Olivieri, Daniel, Novatchkova, Maria, Gruber, Franz Sebastian, Meixner, Katharina, Mechtler, Karl, Stark, Alexander, Sachidanandam, Ravi, Brennecke, Julius
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209783/
https://ncbi.nlm.nih.gov/pubmed/21863019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.308
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