A systematic analysis of Drosophila TUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors

PIWI proteins and their bound PIWI-interacting RNAs (piRNAs) form the core of a gonad-specific small RNA silencing pathway that protects the animal genome against the deleterious activity of transposable elements. Recent studies linked the piRNA pathway to TUDOR biology as TUDOR domains of various p...

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Autors principals: Handler, Dominik, Olivieri, Daniel, Novatchkova, Maria, Gruber, Franz Sebastian, Meixner, Katharina, Mechtler, Karl, Stark, Alexander, Sachidanandam, Ravi, Brennecke, Julius
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209783/
https://ncbi.nlm.nih.gov/pubmed/21863019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.308
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