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Mechanism of transcriptional repression at a bacterial promoter by analysis of single molecules

The molecular basis for regulation of lactose metabolism in Escherichia coli is well studied. Nonetheless, the physical mechanism by which the Lac repressor protein prevents transcription of the lactose promoter remains unresolved. Using multi-wavelength single-molecule fluorescence microscopy, we v...

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Detaylı Bibliyografya
Asıl Yazarlar: Sanchez, Alvaro, Osborne, Melisa L, Friedman, Larry J, Kondev, Jane, Gelles, Jeff
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209775/
https://ncbi.nlm.nih.gov/pubmed/21829165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.273
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