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Mechanism of transcriptional repression at a bacterial promoter by analysis of single molecules
The molecular basis for regulation of lactose metabolism in Escherichia coli is well studied. Nonetheless, the physical mechanism by which the Lac repressor protein prevents transcription of the lactose promoter remains unresolved. Using multi-wavelength single-molecule fluorescence microscopy, we v...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3209775/ https://ncbi.nlm.nih.gov/pubmed/21829165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.273 |
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