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The genome of Th17 cell-inducing segmented filamentous bacteria reveals extensive auxotrophy and adaptations to the intestinal environment

Perturbations of the composition of the symbiotic intestinal microbiota can have profound consequences for host metabolism and immunity. In mice, segmented filamentous bacteria (SFB) direct the accumulation of potentially pro-inflammatory Th17 cells in the intestinal lamina propria. We present the g...

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Detalhes bibliográficos
Main Authors: Sczesnak, Andrew, Segata, Nicola, Qin, Xiang, Gevers, Dirk, Petrosino, Joseph F., Huttenhower, Curtis, Littman, Dan R., Ivanov, Ivaylo I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209701/
https://ncbi.nlm.nih.gov/pubmed/21925113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2011.08.005
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