The genome of Th17 cell-inducing segmented filamentous bacteria reveals extensive auxotrophy and adaptations to the intestinal environment

Perturbations of the composition of the symbiotic intestinal microbiota can have profound consequences for host metabolism and immunity. In mice, segmented filamentous bacteria (SFB) direct the accumulation of potentially pro-inflammatory Th17 cells in the intestinal lamina propria. We present the g...

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Main Authors: Sczesnak, Andrew, Segata, Nicola, Qin, Xiang, Gevers, Dirk, Petrosino, Joseph F., Huttenhower, Curtis, Littman, Dan R., Ivanov, Ivaylo I.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209701/
https://ncbi.nlm.nih.gov/pubmed/21925113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2011.08.005
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