Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells

Commensal microbes can have a substantial impact on autoimmune disorders, but the underlying molecular and cellular mechanisms remain largely unexplored. We report that autoimmune arthritis was strongly attenuated in the K/BxN mouse model under germ-free (GF) conditions, accompanied by reductions in...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Wu, Hsin-Jung, Ivanov, Ivaylo I., Darce, Jaime, Hattori, Kimie, Shima, Tatsuichiro, Umesaki, Yoshinori, Littman, Dan R., Benoist, Christophe, Mathis, Diane
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904693/
https://ncbi.nlm.nih.gov/pubmed/20620945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.06.001
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky