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Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells
Commensal microbes can have a substantial impact on autoimmune disorders, but the underlying molecular and cellular mechanisms remain largely unexplored. We report that autoimmune arthritis was strongly attenuated in the K/BxN mouse model under germ-free (GF) conditions, accompanied by reductions in...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904693/ https://ncbi.nlm.nih.gov/pubmed/20620945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.06.001 |
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