Segmented filamentous bacteria antigens presented by intestinal dendritic cells drive mucosal Th17 cell differentiation

How commensal microbiota contributes to immune cell homeostasis at barrier surfaces is poorly understood. Lamina propria (LP) T helper 17 (Th17) cells participate in mucosal protection and are induced by commensal segmented filamentous bacteria (SFB). Here we show that MHCII-dependent antigen presen...

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Hlavní autoři: Goto, Yoshiyuki, Panea, Casandra, Nakato, Gaku, Cebula, Anna, Lee, Carolyn, Diez, Marta Galan, Laufer, Terri M., Ignatowicz, Leszek, Ivanov, Ivaylo I.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084624/
https://ncbi.nlm.nih.gov/pubmed/24684957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.03.005
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