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DNA Damage Response Signaling Triggers Nuclear Localization of the Chicken Anemia Virus Protein Apoptin

The chicken anemia virus (CAV) protein Apoptin is a small, 13.6-kDa protein that has the intriguing activity of inducing G(2)/M arrest and apoptosis specifically in cancer cells by a mechanism that is independent of p53. The activity of Apoptin is regulated at the level of localization. Whereas Apop...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kucharski, Thomas J., Gamache, Isabelle, Gjoerup, Ole, Teodoro, Jose G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209404/
https://ncbi.nlm.nih.gov/pubmed/21937663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05009-11
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