Interaction of Adenovirus Type 5 E4orf4 with the Nuclear Pore Subunit Nup205 Is Required for Proper Viral Gene Expression

Adenovirus type 5 E4orf4 is a multifunctional protein that regulates viral gene expression. The activities of E4orf4 are mainly mediated through binding to protein phosphatase 2A (PP2A). E4orf4 recruits target phosphoproteins into complexes with PP2A, resulting in dephosphorylation of host factors,...

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Bibliographic Details
Published in:J Virol
Main Authors: Lu, YiQing, Kucharski, Thomas J., Gamache, Isabelle, Blanchette, Paola, Branton, Philip E., Teodoro, Jose G.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249058/
https://ncbi.nlm.nih.gov/pubmed/25210169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00933-14
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