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Activation of the Chicken Anemia Virus Apoptin Protein by Chk1/2 Phosphorylation Is Required for Apoptotic Activity and Efficient Viral Replication

Chicken anemia virus (CAV) is a single-stranded circular DNA virus that carries 3 genes, the most studied of which is the gene encoding VP3, also known as apoptin. This protein has been demonstrated to specifically kill transformed cells while leaving normal cells unharmed in a manner that is indepe...

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Vydáno v:J Virol
Hlavní autoři: Kucharski, Thomas J., Ng, Timothy F., Sharon, David M., Navid-Azarbaijani, Pedram, Tavassoli, Mahvash, Teodoro, Jose G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5044837/
https://ncbi.nlm.nih.gov/pubmed/27512067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00936-16
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