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Multiple DNA Damage Signaling and Repair Pathways Deregulated by Simian Virus 40 Large T Antigen
We demonstrated previously that expression of simian virus 40 (SV40) large T antigen (LT), without a viral origin, is sufficient to induce the hallmarks of a cellular DNA damage response (DDR), such as focal accumulation of γ-H2AX and 53BP1, via Bub1 binding. Here we expand our characterization of L...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2916509/ https://ncbi.nlm.nih.gov/pubmed/20519379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00334-10 |
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