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Replication Stress and Mitotic Dysfunction in Cells Expressing Simian Virus 40 Large T Antigen
We previously demonstrated that simian virus 40 (SV40) large T antigen (LT) binds to the Bub1 kinase, a key regulator of the spindle checkpoint and chromosome segregation. Bub1 mutations or altered expression patterns are linked to chromosome missegregation and are considered to be a driving force i...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3838287/ https://ncbi.nlm.nih.gov/pubmed/24067972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02224-13 |
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