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Residues of the Human Metapneumovirus Fusion (F) Protein Critical for Its Strain-Related Fusion Phenotype: Implications for the Virus Replication Cycle

The paramyxovirus F protein promotes fusion of the viral and cell membranes for virus entry, as well as cell-cell fusion for syncytium formation. Most paramyxovirus F proteins are triggered at neutral pH to initiate membrane fusion. Previous studies, however, demonstrated that human metapneumovirus...

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Main Authors: Mas, Vicente, Herfst, Sander, Osterhaus, Albert D. M. E., Fouchier, Ron A. M., Melero, José A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209396/
https://ncbi.nlm.nih.gov/pubmed/21937649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05485-11
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