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Structure and immunogenicity of pre-fusion-stabilized human metapneumovirus F glycoprotein
Human metapneumovirus (hMPV) is a frequent cause of bronchiolitis in young children. Its F glycoprotein mediates virus–cell membrane fusion and is the primary target of neutralizing antibodies. The inability to produce recombinant hMPV F glycoprotein in the metastable pre-fusion conformation has hin...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5688127/ https://ncbi.nlm.nih.gov/pubmed/29142300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01708-9 |
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