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Engineering, Structure and Immunogenicity of the Human Metapneumovirus F Protein in the Postfusion Conformation

Human metapneumovirus (hMPV) is a paramyxovirus that is a common cause of bronchiolitis and pneumonia in children less than five years of age. The hMPV fusion (F) glycoprotein is the primary target of neutralizing antibodies and is thus a critical vaccine antigen. To facilitate structure-based vacci...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS Pathog
मुख्य लेखकों: Más, Vicente, Rodriguez, Laura, Olmedillas, Eduardo, Cano, Olga, Palomo, Concepción, Terrón, María C., Luque, Daniel, Melero, José A., McLellan, Jason S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017722/
https://ncbi.nlm.nih.gov/pubmed/27611367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005859
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