Engineering, Structure and Immunogenicity of the Human Metapneumovirus F Protein in the Postfusion Conformation

Human metapneumovirus (hMPV) is a paramyxovirus that is a common cause of bronchiolitis and pneumonia in children less than five years of age. The hMPV fusion (F) glycoprotein is the primary target of neutralizing antibodies and is thus a critical vaccine antigen. To facilitate structure-based vacci...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PLoS Pathog
Hauptverfasser: Más, Vicente, Rodriguez, Laura, Olmedillas, Eduardo, Cano, Olga, Palomo, Concepción, Terrón, María C., Luque, Daniel, Melero, José A., McLellan, Jason S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017722/
https://ncbi.nlm.nih.gov/pubmed/27611367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005859
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge