Low-pH-Induced Membrane Fusion Mediated by Human Metapneumovirus F Protein Is a Rare, Strain-Dependent Phenomenon

Membrane fusion promoted by human metapneumovirus (HMPV) fusion (F) protein was suggested to require low pH (R. M. Schowalter, S. E. Smith, and R. E. Dutch, J. Virol. 80:10931-10941, 2006). Using prototype F proteins representing the four HMPV genetic lineages, we detected low-pH-dependent fusion on...

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Main Authors: Herfst, Sander, Mas, Vicente, Ver, Lorena S., Wierda, Rutger J., Osterhaus, Albert D. M. E., Fouchier, Ron A. M., Melero, José A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519679/
https://ncbi.nlm.nih.gov/pubmed/18596097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00472-08
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