Small Hydrophobic Protein of Human Metapneumovirus Does Not Affect Virus Replication and Host Gene Expression In Vitro

Human metapneumovirus (HMPV) encodes a small hydrophobic (SH) protein of unknown function. HMPV from which the SH open reading frame was deleted (HMPVΔSH) was viable and displayed similar replication kinetics, cytopathic effect and plaque size compared with wild type HMPV in several cell-lines. In a...

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Detalhes bibliográficos
Main Authors: de Graaf, Miranda, Herfst, Sander, Aarbiou, Jamil, Burgers, Peter C., Zaaraoui-Boutahar, Fatiha, Bijl, Maarten, van IJcken, Wilfred, Schrauwen, Eefje J. A., Osterhaus, Albert D. M. E., Luider, Theo M., Scholte, Bob J., Fouchier, Ron A. M., Andeweg, Arno C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590193/
https://ncbi.nlm.nih.gov/pubmed/23484037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058572
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