Small Hydrophobic Protein of Human Metapneumovirus Does Not Affect Virus Replication and Host Gene Expression In Vitro

Human metapneumovirus (HMPV) encodes a small hydrophobic (SH) protein of unknown function. HMPV from which the SH open reading frame was deleted (HMPVΔSH) was viable and displayed similar replication kinetics, cytopathic effect and plaque size compared with wild type HMPV in several cell-lines. In a...

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Détails bibliographiques
Auteurs principaux: de Graaf, Miranda, Herfst, Sander, Aarbiou, Jamil, Burgers, Peter C., Zaaraoui-Boutahar, Fatiha, Bijl, Maarten, van IJcken, Wilfred, Schrauwen, Eefje J. A., Osterhaus, Albert D. M. E., Luider, Theo M., Scholte, Bob J., Fouchier, Ron A. M., Andeweg, Arno C.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590193/
https://ncbi.nlm.nih.gov/pubmed/23484037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058572
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