A Double-Inactivated Severe Acute Respiratory Syndrome Coronavirus Vaccine Provides Incomplete Protection in Mice and Induces Increased Eosinophilic Proinflammatory Pulmonary Response upon Challenge

Severe acute respiratory syndrome coronavirus (SARS-CoV) is an important emerging virus that is highly pathogenic in aged populations and is maintained with great diversity in zoonotic reservoirs. While a variety of vaccine platforms have shown efficacy in young-animal models and against homologous...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Bolles, Meagan, Deming, Damon, Long, Kristin, Agnihothram, Sudhakar, Whitmore, Alan, Ferris, Martin, Funkhouser, William, Gralinski, Lisa, Totura, Allison, Heise, Mark, Baric, Ralph S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209347/
https://ncbi.nlm.nih.gov/pubmed/21937658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06048-11
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge