Toll-Like Receptor 3 Signaling via TRIF Contributes to a Protective Innate Immune Response to Severe Acute Respiratory Syndrome Coronavirus Infection

Toll-like receptors (TLRs) are sensors that recognize molecular patterns from viruses, bacteria, and fungi to initiate innate immune responses to invading pathogens. The emergence of highly pathogenic coronaviruses severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Totura, Allison L., Whitmore, Alan, Agnihothram, Sudhakar, Schäfer, Alexandra, Katze, Michael G., Heise, Mark T., Baric, Ralph S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447251/
https://ncbi.nlm.nih.gov/pubmed/26015500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00638-15
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