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THIOREDOXIN REDUCTASE INHIBITION REDUCES RELAXATION BY INCREASING OXIDATIVE STRESS AND S-NITROSYLATION IN MOUSE AORTA

Oxidative stress is well known to lead to vascular dysfunction. Thioredoxin reductase (TrxR) catalyzes the reduction of oxidized thioredoxin (Trx). Reduced Trx plays a role in cellular antioxidative defense as well as in decreasing S-nitrosylation. It is not known whether TrxR affects vascular react...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Choi, Hyehun, Tostes, Rita C., Webb, R. Clinton
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208795/
https://ncbi.nlm.nih.gov/pubmed/21795991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e31822d80a5
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