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MITOCHONDRIAL ALDEHYDE DEHYDROGENASE PREVENTS ROS-INDUCED VASCULAR CONTRACTION IN ANGIOTENSIN II HYPERTENSIVE MICE

BACKGROUND: Mitochondrial aldehyde dehydrogenase (ALDH2) is an enzyme that detoxifies aldehydes to carboxylic acids. ALDH2 deficiency is known to increase oxidative stress, which is the imbalance between reactive oxygen species (ROS) generation and antioxidant defense activity. Increased ROS contrib...

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Detalhes bibliográficos
Main Authors: Choi, Hyehun, Tostes, Rita C., Webb, R. Clinton
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085594/
https://ncbi.nlm.nih.gov/pubmed/21459068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jash.2011.02.005
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