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AUGMENTED S-NITROSYLATION CONTRIBUTES TO IMPAIRED RELAXATION IN ANGIOTENSIN II HYPERTENSIVE MOUSE AORTA: ROLE OF THIOREDOXIN REDUCTASE
Vascular dysfunction, including reduced endothelium-dependent dilation, is a major characteristic of hypertension. We previously investigated that TrxR inhibition impairs vasodilation via soluble guanylyl cyclase S-nitrosylation, but S-nitrosylation and TrxR function are not known in hypertension. W...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4004364/ https://ncbi.nlm.nih.gov/pubmed/22025239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0b013e32834d2554 |
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