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MITOCHONDRIAL ALDEHYDE DEHYDROGENASE PREVENTS ROS-INDUCED VASCULAR CONTRACTION IN ANGIOTENSIN II HYPERTENSIVE MICE
BACKGROUND: Mitochondrial aldehyde dehydrogenase (ALDH2) is an enzyme that detoxifies aldehydes to carboxylic acids. ALDH2 deficiency is known to increase oxidative stress, which is the imbalance between reactive oxygen species (ROS) generation and antioxidant defense activity. Increased ROS contrib...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3085594/ https://ncbi.nlm.nih.gov/pubmed/21459068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jash.2011.02.005 |
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