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THIOREDOXIN REDUCTASE INHIBITION REDUCES RELAXATION BY INCREASING OXIDATIVE STRESS AND S-NITROSYLATION IN MOUSE AORTA
Oxidative stress is well known to lead to vascular dysfunction. Thioredoxin reductase (TrxR) catalyzes the reduction of oxidized thioredoxin (Trx). Reduced Trx plays a role in cellular antioxidative defense as well as in decreasing S-nitrosylation. It is not known whether TrxR affects vascular react...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3208795/ https://ncbi.nlm.nih.gov/pubmed/21795991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e31822d80a5 |
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