Blocking the Leukotriene B4 Receptor 1 Inhibits Late-Phase Airway Responses in Established Disease

Most of the studies investigating the effectiveness of blocking the leukotriene B4 (LTB4) receptor 1 (BLT1) have been performed in models of primary or acute allergen challenge. The role of the LTB4-BLT1 pathway in secondary challenge models, where airway hyperresponsiveness (AHR) and airway inflamm...

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Hlavní autoři: Waseda, Koichi, Miyahara, Nobuaki, Kanehiro, Arihiko, Ikeda, Genyo, Koga, Hikari, Fuchimoto, Yasuko, Kurimoto, Etsuko, Tanimoto, Yasushi, Kataoka, Mikio, Tanimoto, Mitsune, Gelfand, Erwin W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208610/
https://ncbi.nlm.nih.gov/pubmed/21421908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0455OC
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