Pirfenidone Modulates Airway Responsiveness, Inflammation, and Remodeling after Repeated Challenge

We investigated the therapeutic potential of a newly developed antifibrotic agent, pirfenidone, to regulate airway remodeling and the development of allergic airway inflammation and airway hyperresponsiveness after chronic allergen challenge. Administration of pirfenidone after sensitization but dur...

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Detalhes bibliográficos
Main Authors: Hirano, Atsushi, Kanehiro, Arihiko, Ono, Katsuichiro, Ito, Wataru, Yoshida, Akio, Okada, Chiharu, Nakashima, Hiromi, Tanimoto, Yasushi, Kataoka, Mikio, Gelfand, Erwin W., Tanimoto, Mitsune
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643289/
https://ncbi.nlm.nih.gov/pubmed/16675785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0452OC
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