Effect of a retinoid X receptor partial agonist on airway inflammation and hyperresponsiveness in a murine model of asthma

BACKGROUND: Retinoid X receptors (RXRs) are members of the nuclear receptor (NR) superfamily that mediate signaling by 9-cis retinoic acid, a vitamin A (retinol) derivative. RXRs play key roles not only as homodimers but also as heterodimeric partners—e.g., retinoic acid receptors (RARs), vitamin D...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Fujii, Utako, Miyahara, Nobuaki, Taniguchi, Akihiko, Oda, Naohiro, Morichika, Daisuke, Murakami, Etsuko, Nakayama, Hikari, Waseda, Koichi, Kataoka, Mikio, Kakuta, Hiroki, Tanimoto, Mitsune, Kanehiro, Arihiko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5260083/
https://ncbi.nlm.nih.gov/pubmed/28114934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0507-z
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