Coordinate loss of a microRNA and protein-coding gene cooperate in the pathogenesis of 5q− syndrome

Large chromosomal deletions are among the most common molecular abnormalities in cancer, yet the identification of relevant genes has proven difficult. The 5q− syndrome, a subtype of myelodysplastic syndrome (MDS), is a chromosomal deletion syndrome characterized by anemia and thrombocytosis. Althou...

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書誌詳細
主要な著者: Kumar, Madhu S., Narla, Anupama, Nonami, Atsushi, Mullally, Ann, Dimitrova, Nadya, Ball, Brian, McAuley, J. Randall, Poveromo, Luke, Kutok, Jeffrey L., Galili, Naomi, Raza, Azra, Attar, Eyal, Gilliland, D. Gary, Jacks, Tyler, Ebert, Benjamin L.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2011
主題:
Myeloid Neoplasia
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208282/
https://ncbi.nlm.nih.gov/pubmed/21873545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-324715
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