Coordinate loss of a microRNA and protein-coding gene cooperate in the pathogenesis of 5q− syndrome

Large chromosomal deletions are among the most common molecular abnormalities in cancer, yet the identification of relevant genes has proven difficult. The 5q− syndrome, a subtype of myelodysplastic syndrome (MDS), is a chromosomal deletion syndrome characterized by anemia and thrombocytosis. Althou...

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Главные авторы: Kumar, Madhu S., Narla, Anupama, Nonami, Atsushi, Mullally, Ann, Dimitrova, Nadya, Ball, Brian, McAuley, J. Randall, Poveromo, Luke, Kutok, Jeffrey L., Galili, Naomi, Raza, Azra, Attar, Eyal, Gilliland, D. Gary, Jacks, Tyler, Ebert, Benjamin L.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2011
Предметы:
Myeloid Neoplasia
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208282/
https://ncbi.nlm.nih.gov/pubmed/21873545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-324715
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