Cell of origin strongly influences genetic selection in a mouse model of T-ALL

Identifying the normal cell from which a tumor originates is crucial to understanding the etiology of that cancer. However, retrospective identification of the cell of origin in cancer is challenging because of the accumulation of genetic and epigenetic changes in tumor cells. The biologic state of...

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Detalhes bibliográficos
Main Authors: Berquam-Vrieze, Katherine E., Nannapaneni, Kishore, Brett, Benjamin T., Holmfeldt, Linda, Ma, Jing, Zagorodna, Oksana, Jenkins, Nancy A., Copeland, Neal G., Meyerholz, David K., Knudson, C. Michael, Mullighan, Charles G., Scheetz, Todd E., Dupuy, Adam J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208280/
https://ncbi.nlm.nih.gov/pubmed/21828136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-343947
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