SIRT-1 and vascular endothelial dysfunction with ageing in mice and humans

ABSTRACT: We tested the hypothesis that reductions in the cellular deacetylase, sirtuin-1 (SIRT-1), contribute to vascular endothelial dysfunction with ageing via modulation of endothelial nitric oxide synthase (eNOS) acetylation/activation-associated nitric oxide (NO) production. In older (30 month...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Donato, Anthony J, Magerko, Katherine A, Lawson, Brooke R, Durrant, Jessica R, Lesniewski, Lisa A, Seals, Douglas R
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208223/
https://ncbi.nlm.nih.gov/pubmed/21746786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.211219
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados