Salicylate Treatment Improves Age-Associated Vascular Endothelial Dysfunction: Potential Role of Nuclear Factor κB and Forkhead Box O Phosphorylation

We hypothesized that I kappa B kinase (IKK)-mediated nuclear factor kappa B and forkhead BoxO3a phosphorylation will be associated with age-related endothelial dysfunction. Endothelium-dependent dilation and aortic protein expression/phosphorylation were determined in young and old male B6D2F1 mice...

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Bibliographic Details
Main Authors: Lesniewski, Lisa A., Durrant, Jessica R., Connell, Melanie L., Folian, Brian J., Donato, Anthony J., Seals, Douglas R.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
Subjects:
Journal of Gerontology: BIOLOGICAL SCIENCES
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055281/
https://ncbi.nlm.nih.gov/pubmed/21303813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glq233
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