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Short-term Calorie Restriction Reverses Vascular Endothelial Dysfunction in Old Mice by Increasing Nitric Oxide and Reducing Oxidative Stress

To determine if short-term calorie restriction reverses vascular endothelial dysfunction in old mice, old (O, n=30) and young (Y, n=10) male B6D2F1 mice were fed ad libitum (AL) or calorie restricted (CR, ∼30%) for 8 weeks. Ex vivo carotid artery endothelium-dependent dilation (EDD) was impaired in...

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Detalhes bibliográficos
Main Authors: Rippe, Catarina, Lesniewski, Lisa, Connell, Melanie, LaRocca, Thomas, Donato, Anthony, Seals, Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894368/
https://ncbi.nlm.nih.gov/pubmed/20121721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2010.00557.x
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