Life-Long Caloric Restriction Reduces Oxidative Stress and Preserves Nitric Oxide Bioavailability and Function in Arteries of Old Mice

Aging impairs arterial function through oxidative stress and diminished nitric oxide (NO) bioavailability. Life-long caloric restriction (CR) reduces oxidative stress, but its impact on arterial aging is incompletely understood. We tested the hypothesis that life-long CR attenuates key features of a...

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Detalhes bibliográficos
Main Authors: Donato, Anthony J., Walker, Ashley E., Magerko, Katherine, Bramwell, R. Colton, Black, Alex D., Henson, Grant D., Lawson, Brooke R., Lesniewski, Lisa A., Seals, Douglas R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772986/
https://ncbi.nlm.nih.gov/pubmed/23714110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12103
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