Overexpression of serine racemase in retina and overproduction of D-serine in eyes of streptozotocin-induced diabetic retinopathy

BACKGROUND: Recent data indicate that inflammatory mechanisms contribute to diabetic retinopathy (DR). We have determined that serine racemase (SR) expression is increased by inflammatory stimuli including liposaccharide (LPS), amyloid β-peptide (A-beta), and secreted amyloid precursor protein (sAPP...

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Autori principali: Jiang, Haiyan, Fang, Junxu, Wu, Bo, Yin, Guibin, Sun, Lin, Qu, Jia, Barger, Steven W, Wu, Shengzhou
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207970/
https://ncbi.nlm.nih.gov/pubmed/21939517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-119
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