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Roles of quaternary structure and cysteine residues in the activity of human serine racemase

BACKGROUND: D-serine is an important coagonist at the NR1 subunit of the NMDA receptor class of glutamate receptors. It is chiefly synthesized in the CNS by serine racemase (SR). Regulation of SR activity is still poorly understood. As step toward developing reagents and methods for investigating SR...

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Detalhes bibliográficos
Main Authors: Wang, Wei, Barger, Steven W
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252284/
https://ncbi.nlm.nih.gov/pubmed/22151352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-12-63
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